Optimizing preoxygenation in adults

Drawover anaesthesia and preoxygenation.

We have studied the efficacy of preoxygenation using the Triservice Anaesthetic Apparatus (TSA) in healthy patients and found it to be unsatisfactory. An alternative technique suitable for field use was explored. The Mapleson D system (Bain) was found to be suitable for preoxygenation with a fresh gas flow of only 4 litre of oxygen per minute. In a randomized study using only 4 litre of oxygen ...

Optimizing motor Mmemory in healthy adults

Optimizing the initial amikacin dosage in adults.

We report on the pharmacokinetics (PK) and pharmacodynamics (PD) of high-dose (>15 mg/kg of body weight per day) amikacin. A mean (standard deviation [SD]) maximum drug concentration in the serum (Cmax) and 24-h area under the concentration-time curve (AUC24) of 101 (49.4) mg/liter and 600 (387) mg · h/liter, respectively, were observed (n = 73) with 28.0 (8.47) mg/kg/day doses. An initial amik...

Preoxygenation using invasive ventilator in volume control mode in patients with emergency intubation can shorten the time of preoxygenation and improve the quality of preoxygenation

Preoxygenation can rapidly improve oxygenation and enhance the security of endotracheal intubation, so it is very essential before endotracheal intubation. The conventional preoxygenation method self-inflating bag (SIB) is not very effective in case of emergency. So our study aims to find a more effective method of preoxygenation in a critical situation.We retrospectively analyzed data of 105 p...

Preoxygenation in children using expired oxygraphy.

We performed preoxygenation on 25 patients, aged 1-12 yr. End-tidal oxygen sampling was used to find the duration of preoxygenation required to reach an end-tidal oxygen fraction of 0.9. All children reached this end-point within 80 s, which was markedly more rapid than that observed in adult subjects. The clinical applications of this form of monitoring in children are discussed.